Multiple experiments with a single individual
2004-01-08 18:08:02 GMT
Frederic,
I have a question about how to define the levels in the simulation input file to implement a hierarchical population model. I have data on several individuals, and multiple experiments were performed per individual. Suppose I have Experiments A through Z. Then my file might look like the following.
Level {
Distributions for population means
Distributions for population variances
Likelihood definition
Level {
Distributions at the subject level
Experiment { A
Individual 1 experiment
}
Experiment { B
Individual 2 experiment
}
…
Experiment { Z
Individual N experiment
}
}
}
MCSim “clones” the subject level distributions, and each experiment would receive a different parameter vector. Suppose experiments B and C were performed on the same individual. How do I tell MCSim to use the same parameters for experiments B and C? Should I enclose them in a third level statement, such as the following?
Level {
Distributions for population means
Distributions for population variances
Likelihood definition
Level {
Distributions at the subject level
Experiment { A
Individual 1 experiment
}
Level { #Open level for individual in experiments B and C
Experiment { B
Individual 2 experiment number 1
}
Experiment { C
Individual 2 experiment number 2
}
} #Close level for individual in experiments B and C
…
Experiment { Z
Individual N experiment
}
}
}
Thank you,
Eric Hack
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